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Today’s Health News
Overall Burden of CVD Remained High in United Kingdom in 2000 to 2019
Incidence of all 10 prespecified CVDs decreased, but diagnoses of cardiac arrhythmias, valve disease, and thromboembolic diseases increased
Recommendations Issued for Advanced Imaging for Pediatric Patients in ED
Pediatric emergency departments should ensure appropriate imaging resources are available or have transfer protocols in place
Histologic Response Up With Benralizumab for Eosinophilic Esophagitis
Significantly more patients had histologic response with benralizumab than placebo, but no significant difference seen in dysphagia symptoms
ADA: Bisphenol A Linked to Reduced Peripheral Insulin Sensitivity
Significant decrease seen in peripheral insulin sensitivity with four-day energy balance diet plus oral BPA administration
Immunoglobulin Replacement Therapy Beneficial for Blood Cancers
Reduction seen in hypogammaglobulinemia, infections or severe infections, and associated antimicrobial use
Exercise + GLP-1 RA Effective for Weight Loss While Preserving BMD
Greatest total estimated mean change in weight loss with combination of exercise and liraglutide
ADA: Inhaled Insulin Shows Promise for Adults With Type 1 Diabetes
Authors say inhaled insulin may provide convenient alternative delivery method
Dupilumab Ups Histologic Response for Pediatric Eosinophilic Esophagitis
Significant improvements seen in histologic, endoscopic, and transcriptomic measures in higher-exposure dupilumab regimen
PIK3CA Could Guide Use of COX-2 Inhibitors in Treatment for Colon Cancer
Patients with stage III resected colon cancer with PIK3CA gain-of-function mutations treated with celecoxib had improved DFS, OS
Rare Predicted Loss-of-Function Variants, Polygenic Risk Score Linked to Risk of A-Fib
Odds ratio of 7.08 for atrial fibrillation for rare pLOF variants combined with high polygenic risk score