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2004 to 2021 Saw Increase in Distant-Stage Breast Cancer Incidence

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Significant increase seen in incidence rates at presentation for women overall, and for those aged 20 to 39, 40 to 74, and 75 years or older

By Elana Gotkine HealthDay Reporter

THURSDAY, Dec. 12, 2024 (HealthDay News) — During 2004 to 2021, there was an increase in distant-stage breast cancer incidence rates at presentation, according to a study published online Dec. 10 in Radiology.

R. Edward Hendrick, Ph.D., and Debra L. Monticciolo, M.D., from the University of Colorado School of Medicine in Aurora, examined trends in distant-stage breast cancer incidence using the latest data from the Surveillance, Epidemiology, and End Results database. Stage-specific breast cancer incidence rates were analyzed from January 2004 to December 2021 in a retrospective study of 71 to 80 million women annually.

The researchers found a significant increase in distant-stage breast cancer incidence rates at presentation for U.S. women overall, with an annual percentage change (APC) of 1.16 percent during 2004 to 2021. For women aged 20 to 39 years and for women aged 75 years or older, distant-stage disease increased consistently (APCs, 2.91 and 1.44 percent, respectively). For women aged 40 to 74 years, the distant-stage breast cancer incidence rates increased with APCs of 2.10 and 2.73 percent during 2004 to 2010 and 2018 to 2021, respectively. The COVID-19-linked interruption of care in 2020 affected distant-stage breast cancer detection, especially among older women from racial and ethnic minority groups. During 2004 to 2021, the incidence of distant-stage breast cancer increased for Asian, Black, and Hispanic women (APCs, 2.90, 0.86, and 1.56 percent, respectively), and during 2004 to 2019, the incidence increased for Native American women (APC, 3.86 percent).

“Much work is needed to improve early detection and ensure that all women have sustained access to care,” the authors write.

One author disclosed ties to the medical device industry.

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