Higher dietary calcium intake linked to increased risk of BPH after adjustment for all covariates
By Elana Gotkine HealthDay Reporter
TUESDAY, June 24, 2025 (HealthDay News) — There is a significant positive association between dietary calcium intake and benign prostatic hyperplasia (BPH), according to a study published online May 30 in Translational Andrology and Urology.
Hongyuan Chang, from Xiyuan Hospital of China Academy of Chinese Medical Sciences in Beijing, and colleagues used data from the National Health and Nutrition Examination Survey conducted from 2003 to 2008 to examine the association between dietary calcium intake and the risk of BPH. Data were included for 590 men aged 40 years and older, of whom 138 had BPH.
The researchers found that a higher dietary calcium intake was associated with increased risk of BPH after adjustment for all covariates (odds ratio, 1.05). In subgroup analyses, the investigators found that the association was more pronounced among individuals aged at least 60 years, those with poverty income ratio greater than 3.5, and those without hypertension.
“Our study revealed a positive correlation between dietary calcium intake and BPH, accompanied by a significant dose-response trend,” the authors write. “Beyond the inflection point, a positive correlation between dietary calcium intake and BPH was observed, suggesting a positive association between higher calcium intake and the occurrence of BPH.”
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