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Today’s Health News

FDA Approves Injectable Ocrevus Zunovo for Relapsing, Progressive MS

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Phase 3 data show efficacy and safety profile similar to intravenous administration

U.S. Suicide Rate Increased to 14.2 Per 100,000 in 2022

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Decline in age-adjusted suicide rate from 2018 to 2020 followed by increases in 2021 and 2022

FDA Approves Bimzelx for Three New Indications

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New indications include active psoriatic arthritis, nonradiographic axial spondyloarthritis with objective signs of inflammation, and ankylosing spondylitis

Digital Mental Health Games Improve Psychological Outcomes in Youth

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Findings seen for attention-deficit/hyperactivity disorder or depressive disorder

Global Prevalence of Congenital Heart Disease at High Altitude ~9 Percent

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However, authors note this is likely underestimated and underdiagnosed

Today’s Health News

Family Medicine-Only Staffing at Birthing Hospitals Tied to Fewer C-Sections

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Additionally, family medicine-only staffed hospitals have stronger nursing-rated safety culture

Non-Hispanic Black Patients Have Disparities in HCT Use for Hematologic Cancers

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For AML and MDS, lower utilization seen for non-Hispanic Black patients compared with other groups

Prenatal Exposure to Pandemic Milieu, Maternal SARS-CoV-2 Does Not Increase Autism Risk

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No increased rates of positive M-CHAT-R screening seen for offspring

Melanoma Risk Increased After Radioactive Iodine Treatment for Primary Thyroid Cancer

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Standardized incidence ratios elevated for all nonkeratinocyte skin cancers, melanoma

Fidanacogene Elaparvovec Superior to Prophylaxis for Hemophilia B

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Adeno-associated virus gene-therapy vector for hemophilia B superior for reducing annualized bleeding rate

Anti-CD20 Therapy Shows No Effect on Disability Progression in MS

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Anti-CD20-treated primary progressive multiple sclerosis patients have higher risk for serious infection

Semaglutide Beneficial for Hidradenitis Suppurativa in Patients With Obesity

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Semaglutide added to standard treatments yields improvement in quality of life, reduction in flares

Risk for Stroke, TIA Increased in Adults With Sickle Cell Disease

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Cumulative incidence of first ischemic stroke was 2.1 percent by age 20 years, 13.5 percent by age 60 years

Wearable Tied to Better Physical Activity Recovery Following Lung Cancer Surgery

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Better outcomes also seen for dyspnea compared with controls

Transgender, Gender-Diverse Youth Have Five Times Higher Positive Suicide Screens in ED

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Active suicidal ideation higher for cisgender males than females