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Timing of Exercise Significant for Obesity, Metabolic Impairment

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Beneficial effect on glucose hemostasis seen for accumulation of more MVPA in the evening for sedentary adults

By Elana Gotkine HealthDay Reporter

THURSDAY, June 20, 2024 (HealthDay News) — For sedentary adults with obesity/overweight and metabolic impairments, the timing of moderate-to-vigorous physical activity (MVPA) is significant, with a beneficial effect on glucose homeostasis for accumulation of more MVPA in the evening, according to a study published online June 10 in Obesity.

Antonio Clavero-Jimeno, from the University of Granada in Spain, and colleagues examined the impact of lifestyle MVPA timing on daily glycemic control in 186 sedentary adults with overweight/obesity and metabolic impairments. During a 14-day period, MVPA and glucose patterns were simultaneously monitored. Each day was classified as inactive if no MVPA was accumulated; as morning, afternoon, or evening if >50 percent of the MVPA minutes were accumulated between 0600 and 1200, 1200 and 1800, or 1800 and 0000 hours, respectively; or mixed if none of the time windows accounted for >50 percent of the daily MVPA.

The researchers found that compared with being inactive, accumulating >50 percent of total MVPA in the evening was associated with lower 24-hour, diurnal, and nocturnal mean glucose levels (mean differences, −1.26, −1.10, and −2.16 mg/dL, respectively). In participants with impaired glucose regulation, this association was stronger. In both men and women, the pattern of these associations was similar.

“The timing of lifestyle MVPA is significant and … accumulating most MVPA during the evening is associated with lower glucose levels in adults with overweight/obesity and metabolic impairments,” the authors write. “These findings highlight the promising area of MVPA timing as a novel approach to improve metabolic health in people at risk of developing cardiovascular diseases.”

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